The 18th ranked Marquette Golden Eagles got 23 points from Darius Johnson-Odom and knocked off the DePaul Blue Demons 89-76 in Big East action.
The Golden Eagles used a 16-3 run to open the second half to pull away.
Cleveland Melvin had 22 to lead DePaul, but the Blue Demons have now dropped 36 straight games against ranked opponents dating back to January of 2008.
Jamil Wilson added 18 points, Vander Blue 16 and Jae Crowder 14 for Marquette.
The Golden Eagles are off until Saturday when they host Cincinnati.
